Riff Randall is a passionate Ramones fan. Riff has composed a song for her idols and hopes to present her composition to them in person as soon as they come to her town for a concert. Taking pals Tom and Eaglebower with her, Riff heads to the concert to meet her idols in person. But the newly appointed principal of the Vince Lombardi School, where Riff attends, the famously stern Ms. Togar declares a war of annihilation on rock ‘n’ roll. Togar goes so far as to try to scientifically prove the harmful effects that rock ‘n’ roll has on living things. To do this, she forces lab mice to listen to Ramones music. After some time has passed, the mice rapidly degenerate, wear little leather jackets, and eventually die from exposure to the horrible music. When teachers and parents make a bonfire out of vinyl disks of rock music, the angry children decide to teach the adults a lesson. With the help of the Ramones, they take over the school and the rock and roll catavasy begins.